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Gene: Sord (sorbitol dehydrogenase) Rattus norvegicus
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Symbol: Sord
Name: sorbitol dehydrogenase
Description: Exhibits identical protein binding activity and zinc ion binding activity. Involved in several processes, including response to cadmium ion; response to copper ion; and response to osmotic stress. Predicted to localize to several cellular components, including the extracellular exosome; mitochondrion; and motile cilium. Used to study diabetic neuropathy. Orthologous to human SORD (sorbitol dehydrogenase); PARTICIPATES IN fructose and mannose metabolic pathway; fructosuria pathway; hereditary fructose intolerance syndrome pathway; INTERACTS WITH (+)-schisandrin B; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,1,2-trichloroethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: L-iditol 2-dehydrogenase; polyol dehydrogenase; SDH; XDH; xylitol dehydrogenase
Orthologs:
Homo sapiens (human) : SORD (sorbitol dehydrogenase)  HGNC  Alliance
Mus musculus (house mouse) : Sord (sorbitol dehydrogenase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sord (sorbitol dehydrogenase)
Pan paniscus (bonobo/pygmy chimpanzee) : SORD (sorbitol dehydrogenase)
Canis lupus familiaris (dog) : SORD (sorbitol dehydrogenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sord (sorbitol dehydrogenase)
Sus scrofa (pig) : SORD (sorbitol dehydrogenase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03114,176,127 - 114,207,368 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3114,176,309 - 114,207,366 (+)Ensembl
Rnor_5.03120,716,804 - 120,746,951 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43109,016,830 - 109,048,446 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13108,922,464 - 108,953,299 (+)NCBI
Celera3108,082,883 - 108,113,935 (+)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Sord
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3734
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.