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Gene: Sp4 (Sp4 transcription factor) Rattus norvegicus
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Symbol: Sp4
Name: Sp4 transcription factor
Description: Exhibits DNA binding activity and DNA-binding transcription factor activity. Predicted to be involved in regulation of heart contraction and regulation of transcription by RNA polymerase II. Localizes to the nucleus. Human ortholog(s) of this gene implicated in congenital heart disease and dilated cardiomyopathy. Orthologous to human SP4 (Sp4 transcription factor); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: HF-1b; HF-1b zinc finger protein; Trans-acting transcription factor 4; transcription factor Sp4
Orthologs:
Homo sapiens (human) : SP4 (Sp4 transcription factor)  HGNC  Alliance
Mus musculus (house mouse) : Sp4 (trans-acting transcription factor 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sp4 (Sp4 transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : SP4 (Sp4 transcription factor)
Canis lupus familiaris (dog) : SP4 (Sp4 transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sp4 (Sp4 transcription factor)
Sus scrofa (pig) : SP4 (Sp4 transcription factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.06146,135,877 - 146,201,344 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06155,047,728 - 155,113,698 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46145,553,512 - 145,619,389 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16145,559,698 - 145,620,144 (-)NCBI
Celera6136,844,006 - 136,908,926 (-)NCBICelera
Cytogenetic Map6q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Sp4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3741
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.