Gene: Spn (sialophorin) Rattus norvegicus
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Symbol: Spn
Name: sialophorin
Description: Exhibits protein domain specific binding activity; involved in several processes, including T cell receptor signaling pathway, chronic inflammatory response, and monocyte activation; localizes to the cell surface, cleavage furrow, and microvillus; orthologous to human SPN (sialophorin); INTERACTS WITH (RS)-amphetamine; 4-amino-2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Cd43; gpL115; leukocyte sialoglycoprotein; Leukosialin; leukosianin; Lsn; Lsn1; Sialophorin (gpL115 leukosianin CD43); Sialophorin (gpL115, leukosianin, CD43); W3/13 antigen
Orthologs:
Homo sapiens (human) : SPN (sialophorin)  HGNC  Alliance
Mus musculus (house mouse) : Spn (sialophorin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spn (sialophorin)
Pan paniscus (bonobo/pygmy chimpanzee) : SPN (sialophorin)
Canis lupus familiaris (dog) : SPN (sialophorin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spn (sialophorin)
Sus scrofa (pig) : SPN (sialophorin)
more info ...
Is Marker For: QTLs:   Bp43   Pancm1   Iddm10   Bp84  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01198,572,999 - 198,585,664 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01205,563,659 - 205,576,290 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41186,388,120 - 186,391,887 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11186,538,248 - 186,541,733 (-)NCBI
Celera1179,399,985 - 179,404,212 (-)NCBICelera
Cytogenetic Map1q37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Spn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3750
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.