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Gene: Sptbn2 (spectrin, beta, non-erythrocytic 2) Rattus norvegicus
Symbol: Sptbn2
Name: spectrin, beta, non-erythrocytic 2
Description: Predicted to be a structural constituent of synapse. Involved in cellular response to ethanol and synaptic vesicle exocytosis. Localizes to several cellular components, including Golgi membrane; cytoplasmic vesicle; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 14 and spinocerebellar ataxia type 5. Orthologous to human SPTBN2 (spectrin beta, non-erythrocytic 2); INTERACTS WITH (+)-schisandrin B; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: beta SpIII sigma 1; beta-III spectrin; beta-spectrin 3; glutamate transporter EAAT4-associated protein 41; spectrin beta 3; spectrin beta chain, brain 2; spectrin beta chain, non-erythrocytic 2; spectrin, non-erythroid beta chain 2; spectrin-like protein GTRAP41; SPNB-3; Spnb3
Homo sapiens (human) : SPTBN2 (spectrin beta, non-erythrocytic 2)  HGNC  Alliance
Mus musculus (house mouse) : Sptbn2 (spectrin beta, non-erythrocytic 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sptbn2 (spectrin beta, non-erythrocytic 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SPTBN2 (spectrin beta, non-erythrocytic 2)
Canis lupus familiaris (dog) : SPTBN2 (spectrin beta, non-erythrocytic 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sptbn2 (spectrin beta, non-erythrocytic 2)
Sus scrofa (pig) : SPTBN2 (spectrin beta, non-erythrocytic 2)
Chlorocebus sabaeus (African green monkey) : SPTBN2 (spectrin beta, non-erythrocytic 2)
Heterocephalus glaber (naked mole-rat) : Sptbn2 (spectrin beta, non-erythrocytic 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01219,964,429 - 220,006,811 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1219,964,429 - 220,005,068 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01226,828,798 - 226,870,783 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41207,318,258 - 207,358,896 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11207,471,710 - 207,512,349 (+)NCBI
Celera1199,543,481 - 199,584,122 (+)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Sptbn2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3751
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.