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Gene: Sqle (squalene epoxidase) Rattus norvegicus
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Symbol: Sqle
Name: squalene epoxidase
Description: Exhibits squalene monooxygenase activity. Involved in cellular aromatic compound metabolic process; cholesterol metabolic process; and response to organic substance. Localizes to the intracellular membrane-bounded organelle. Orthologous to human SQLE (squalene epoxidase); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; INTERACTS WITH 1-(3-(trifluoromethyl)phenyl)piperazine; 1-benzylpiperazine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: SE; squalene monooxygenase
Orthologs:
Homo sapiens (human) : SQLE (squalene epoxidase)  HGNC  Alliance
Mus musculus (house mouse) : Sqle (squalene epoxidase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sqle (squalene epoxidase)
Pan paniscus (bonobo/pygmy chimpanzee) : SQLE (squalene epoxidase)
Canis lupus familiaris (dog) : SQLE (squalene epoxidase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sqle (squalene epoxidase)
Sus scrofa (pig) : SQLE (squalene epoxidase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0799,609,929 - 99,624,803 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07100,197,094 - 100,211,968 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4796,096,897 - 96,111,772 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1796,130,995 - 96,146,001 (+)NCBI
Celera787,631,412 - 87,646,286 (+)NCBICelera
Cytogenetic Map7q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Sqle
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3755
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.