Gene: Abcc8 (ATP binding cassette subfamily C member 8) Rattus norvegicus
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Symbol: Abcc8
Name: ATP binding cassette subfamily C member 8
Description: Predicted to contribute to potassium channel activity; involved in several processes, including cellular glucose homeostasis, cellular response to organic substance, and learning or memory; localizes to the inward rectifying potassium channel, sarcolemma, and synaptic vesicle membrane; colocalizes with the mitochondrion; used to study brain edema, cardiac arrest, hypoglycemia, and middle cerebral artery infarction; biomarker of sciatic neuropathy, status epilepticus, and visual epilepsy; orthologous to human ABCC8 (ATP binding cassette subfamily C member 8); PARTICIPATES IN diabetes mellitus pathway; acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ATP-binding cassette sub-family C (CFTR/MRP) member 8; ATP-binding cassette sub-family C member 8; ATP-binding cassette subfamily C (CFTR/MRP) member 8; ATP-binding cassette transporter sub-family C member 8; ATP-binding cassette, sub-family C (CFTR/MRP), member 8; ATP-binding cassette, subfamily C (CFTR/MRP), member 8; sulfonylurea receptor; sulfonylurea receptor 1; sulphonylurea receptor 1; Sur; Sur1
Orthologs:
Homo sapiens (human) : ABCC8 (ATP binding cassette subfamily C member 8)  HGNC  Alliance
Mus musculus (house mouse) : Abcc8 (ATP-binding cassette, sub-family C (CFTR/MRP), member 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abcc8 (ATP binding cassette subfamily C member 8)
Pan paniscus (bonobo/pygmy chimpanzee) : ABCC8 (ATP binding cassette subfamily C member 8)
Canis lupus familiaris (dog) : ABCC8 (ATP binding cassette subfamily C member 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abcc8 (ATP binding cassette subfamily C member 8)
Sus scrofa (pig) : ABCC8 (ATP binding cassette subfamily C member 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01102,110,708 - 102,191,287 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01103,194,473 - 103,275,508 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4196,622,574 - 96,703,723 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1196,700,590 - 96,781,880 (-)NCBI
Celera190,849,685 - 90,928,224 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Abcc8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3786
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.