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Gene: Abcc9 (ATP binding cassette subfamily C member 9) Rattus norvegicus
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Symbol: Abcc9
Name: ATP binding cassette subfamily C member 9
Description: Exhibits several functions, including identical protein binding activity; potassium channel regulator activity; and sulfonylurea receptor activity. Predicted to contribute to potassium channel activity. Involved in potassium ion import across plasma membrane and response to drug. Localizes to the T-tubule; cytoplasm; and inward rectifying potassium channel. Biomarker of hypertension and sciatic neuropathy. Human ortholog(s) of this gene implicated in dilated cardiomyopathy; dilated cardiomyopathy 1O; familial atrial fibrillation; and hypertrichotic osteochondrodysplasia Cantu type. Orthologous to human ABCC9 (ATP binding cassette subfamily C member 9); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ATP-binding cassette sub-family C member 9; ATP-binding cassette transporter sub-family C member 9; ATP-binding cassette, sub-family C (CFTR/MRP), member 9; ATP-binding cassette, sub-family C, member 9-like; ATP-binding cassette, subfamily C (CFTR/MRP), member 9; LOC100360403; Sulfonylurea receptor 2; Sur2
Orthologs:
Homo sapiens (human) : ABCC9 (ATP binding cassette subfamily C member 9)  HGNC  Alliance
Mus musculus (house mouse) : Abcc9 (ATP-binding cassette, sub-family C (CFTR/MRP), member 9)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abcc9 (ATP binding cassette subfamily C member 9)
Pan paniscus (bonobo/pygmy chimpanzee) : ABCC9 (ATP binding cassette subfamily C member 9)
Canis lupus familiaris (dog) : ABCC9 (ATP binding cassette subfamily C member 9)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abcc9 (ATP binding cassette subfamily C member 9)
Sus scrofa (pig) : ABCC9 (ATP binding cassette subfamily C member 9)
more info ...
Allele / Splice: Abcc9_v1   Abcc9_v2  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04176,806,098 - 176,928,540 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04241,019,980 - 241,139,051 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44180,165,979 - 180,236,791 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11533,877,146 - 33,883,992NCBI
Celera4164,064,977 - 164,186,502 (-)NCBICelera
Cytogenetic Map4q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Abcc9
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3787
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.