Gene: Tbxas1 (thromboxane A synthase 1) Rattus norvegicus
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Symbol: Tbxas1
Name: thromboxane A synthase 1
Description: Predicted to have thromboxane-A synthase activity; involved in several processes, including cellular chloride ion homeostasis, positive regulation of vasoconstriction, and response to ethanol; predicted to localize to the endoplasmic reticulum membrane and integral component of membrane; used to study several diseases, including artery disease (multiple), brain infarction, glomerulonephritis (multiple), and thrombosis; biomarker of hydronephrosis; orthologous to human TBXAS1 (thromboxane A synthase 1); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; INTERACTS WITH (RS)-amphetamine; 17alpha-ethynylestradiol; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cytochrome P450 5A1; ThromboxA ane synthase 1; thromboxane A synthase 1, platelet; thromboxane-A synthase; TXA synthase; TXS
Orthologs:
Homo sapiens (human) : TBXAS1 (thromboxane A synthase 1)  HGNC  Alliance
Mus musculus (house mouse) : Tbxas1 (thromboxane A synthase 1, platelet)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbxas1 (thromboxane A synthase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TBXAS1 (thromboxane A synthase 1)
Canis lupus familiaris (dog) : TBXAS1 (thromboxane A synthase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbxas1 (thromboxane A synthase 1)
Sus scrofa (pig) : TBXAS1 (thromboxane A synthase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0466,624,181 - 66,846,745 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0466,481,238 - 66,651,613 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4466,502,253 - 66,677,538 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1466,778,382 - 66,953,668 (+)NCBI
Celera462,678,426 - 62,850,218 (+)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Tbxas1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3826
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.