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Gene: Tf (transferrin) Rattus norvegicus
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Symbol: Tf
Name: transferrin
Description: Exhibits ferric iron binding activity. Involved in several processes, including cellular response to cAMP; cellular response to follicle-stimulating hormone stimulus; and positive regulation of nervous system development. Localizes to the basement membrane; cell tip; and extracellular space. Used to study hepatitis. Biomarker of anemia and obesity. Human ortholog(s) of this gene implicated in anemia; atransferrinemia; glucose metabolism disease (multiple); iron deficiency anemia; and restless legs syndrome. Orthologous to human TF (transferrin); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; hypoxia inducible factor pathway; iron uptake pathway; INTERACTS WITH (+)-schisandrin B; (RS)-amphetamine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: beta-1 metal-binding globulin; liver regeneration-related protein LRRG03; MGC93500; serotransferrin; siderophilin; Tfn; Trf
Orthologs:
Homo sapiens (human) : TF (transferrin)  HGNC  Alliance
Mus musculus (house mouse) : Trf (transferrin)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : TF (transferrin)
Canis lupus familiaris (dog) : LOC477072 (serotransferrin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tf (transferrin)
Sus scrofa (pig) : TF (transferrin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08111,694,570 - 111,721,275 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08111,085,984 - 111,112,688 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48108,217,774 - 108,244,487 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18108,237,229 - 108,263,942 (-)NCBI
Celera8103,167,171 - 103,194,045 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tf
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3845
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.