Gene: Timp3 (TIMP metallopeptidase inhibitor 3) Rattus norvegicus
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Symbol: Timp3
Name: TIMP metallopeptidase inhibitor 3
Description: Predicted to have metalloendopeptidase inhibitor activity, protease binding activity, and zinc ion binding activity; involved in several processes, including aging, central nervous system development, and negative regulation of proteolysis; localizes to the cytoplasm; orthologous to human TIMP3 (TIMP metallopeptidase inhibitor 3); PARTICIPATES IN angiotensin II signaling pathway via AT2 receptor; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: metalloproteinase inhibitor 3; TIMP-3; tissue inhibitor of metalloproteinase 3; tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory); tissue inhibitor of metalloproteinases 3
Orthologs:
Homo sapiens (human) : TIMP3 (TIMP metallopeptidase inhibitor 3)  HGNC  Alliance
Mus musculus (house mouse) : Timp3 (tissue inhibitor of metalloproteinase 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Timp3 (TIMP metallopeptidase inhibitor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TIMP3 (TIMP metallopeptidase inhibitor 3)
Canis lupus familiaris (dog) : TIMP3 (TIMP metallopeptidase inhibitor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Timp3 (TIMP metallopeptidase inhibitor 3)
Sus scrofa (pig) : TIMP3 (TIMP metallopeptidase inhibitor 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0723,543,125 - 23,594,170 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0723,693,364 - 23,744,404 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4719,677,144 - 19,727,072 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1719,686,693 - 19,737,062 (-)NCBI
Celera714,761,240 - 14,810,915 (-)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Timp3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3865
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.