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Gene: Tpi1 (triosephosphate isomerase 1) Rattus norvegicus
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Symbol: Tpi1
Name: triosephosphate isomerase 1
Description: Exhibits triose-phosphate isomerase activity. Involved in carbohydrate metabolic process. Localizes to the cytosol and nucleus. Biomarker of ocular hypertension. Human ortholog(s) of this gene implicated in carbohydrate metabolic disorder and triosephosphate isomerase deficiency. Orthologous to human TPI1 (triosephosphate isomerase 1); PARTICIPATES IN Fanconi syndrome pathway; fructose and mannose metabolic pathway; fructose-1,6-bisphosphatase deficiency pathway; INTERACTS WITH (+)-schisandrin B; (RS)-amphetamine; 1,2,4-trimethylbenzene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: methylglyoxal synthase; MGC156639; TIM; Tpi; triose-phosphate isomerase; triosephosphate isomerase
Orthologs:
Homo sapiens (human) : TPI1 (triosephosphate isomerase 1)  HGNC  Alliance
Mus musculus (house mouse) : Tpi1 (triosephosphate isomerase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tpi1 (triosephosphate isomerase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TPI1 (triosephosphate isomerase 1)
Canis lupus familiaris (dog) : TPI1 (triosephosphate isomerase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tpi1 (triosephosphate isomerase 1)
Sus scrofa (pig) : TPI1 (triosephosphate isomerase 1)
more info ...
Related Pseudogenes: LOC681129  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04157,328,375 - 157,331,905 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04224,345,971 - 224,349,501 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,933,341 - 160,936,871 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14161,178,382 - 161,181,807 (-)NCBI
Celera4146,353,273 - 146,356,791 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tpi1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3896
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.