Gene: Clu (clusterin) Rattus norvegicus
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Symbol: Clu
Name: clusterin
Description: Exhibits protein N-terminus binding activity; involved in several processes, including aging, cellular response to growth factor stimulus, and endocrine pancreas development; localizes to several cellular components, including the aggresome, extracellular space, and growth cone; predicted to colocalize with several cellular components, including the cell periphery, collagen-containing extracellular matrix, and cytoskeleton; used to study atherosclerosis and renal fibrosis; biomarker of several diseases, including anti-basement membrane glomerulonephritis, brain ischemia, kidney failure (multiple), prostate disease (multiple), and proteinuria; orthologous to human CLU (clusterin); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: APOJ; CLI; DAG; dimeric acid glycoprotein; RATTRPM2B; SGP-2; SGP2; SP-40; SP40; sulfated glycoprotein 2; testosterone repressed prostate message 2; testosterone-repressed prostate message; testostrone-repressed prostate message 2; TRPM-2; Trpm2; TRPM2B; Trpmb
Orthologs:
Homo sapiens (human) : CLU (clusterin)  HGNC  Alliance
Mus musculus (house mouse) : Clu (clusterin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Clu (clusterin)
Pan paniscus (bonobo/pygmy chimpanzee) : CLU (clusterin)
Canis lupus familiaris (dog) : CLU (clusterin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clu (clusterin)
Sus scrofa (pig) : CLU (clusterin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01542,626,612 - 42,665,858 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01548,926,511 - 48,965,757 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41545,365,779 - 45,405,314 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11545,381,558 - 45,421,094 (+)NCBI
Celera1539,832,711 - 39,871,901 (+)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Clu
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3907
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.