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Gene: Tsg101 (tumor susceptibility 101) Rattus norvegicus
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Symbol: Tsg101
Name: tumor susceptibility 101
Description: Exhibits nuclear receptor transcription coactivator activity. Involved in endosome to lysosome transport and protein monoubiquitination. Localizes to the endosome membrane and nucleus. Human ortholog(s) of this gene implicated in breast cancer; breast carcinoma; cervix carcinoma; endometrial adenocarcinoma; and prostate cancer. Orthologous to human TSG101 (tumor susceptibility 101); PARTICIPATES IN autophagy pathway; endocytosis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; Brodifacoum.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ESCRT-I complex subunit TSG101; Rw; tumor supressor; tumor susceptibility gene 101
Orthologs:
Homo sapiens (human) : TSG101 (tumor susceptibility 101)  HGNC  Alliance
Mus musculus (house mouse) : Tsg101 (tumor susceptibility gene 101)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tsg101 (tumor susceptibility 101)
Pan paniscus (bonobo/pygmy chimpanzee) : TSG101 (tumor susceptibility 101)
Canis lupus familiaris (dog) : TSG101 (tumor susceptibility 101)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tsg101 (tumor susceptibility 101)
Sus scrofa (pig) : TSG101 (tumor susceptibility 101)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01102,941,151 - 102,971,017 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1102,941,231 - 102,970,950 (-)Ensembl
Rnor_5.01104,015,969 - 104,044,641 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4197,445,040 - 97,475,141 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1197,523,152 - 97,553,252 (-)NCBI
Celera191,659,356 - 91,689,173 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tsg101
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3909
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.