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Gene: Tshb (thyroid stimulating hormone subunit beta) Rattus norvegicus
Symbol: Tshb
Name: thyroid stimulating hormone subunit beta
CRRD ID: 3910
Description: Predicted to contribute to hormone activity. Involved in response to calcium ion; response to estrogen; and response to vitamin A. Predicted to localize to cytoplasm and extracellular space. Human ortholog(s) of this gene implicated in congenital nongoitrous hypothyroidism 4 and hypothyroidism. Orthologous to human TSHB (thyroid stimulating hormone subunit beta); PARTICIPATES IN autoimmune thyroiditis pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: thyroid stimulating hormone beta subunit; thyroid stimulating hormone, beta; thyroid stimulating hormone, beta subunit; thyroid-stimulating hormone subunit beta; thyrotropin beta chain; thyrotropin subunit beta; TSH-B; TSH-beta
Homo sapiens (human) : TSHB (thyroid stimulating hormone subunit beta)  HGNC  Alliance
Mus musculus (house mouse) : Tshb (thyroid stimulating hormone, beta subunit)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tshb (thyroid stimulating hormone subunit beta)
Pan paniscus (bonobo/pygmy chimpanzee) : TSHB (thyroid stimulating hormone subunit beta)
Canis lupus familiaris (dog) : TSHB (thyroid stimulating hormone subunit beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tshb (thyroid stimulating hormone subunit beta)
Sus scrofa (pig) : TSHB (thyroid stimulating hormone subunit beta)
Chlorocebus sabaeus (African green monkey) : TSHB (thyroid stimulating hormone subunit beta)
Heterocephalus glaber (naked mole-rat) : Tshb (thyroid stimulating hormone subunit beta)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02205,207,799 - 205,215,199 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2205,207,799 - 205,212,681 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02224,638,392 - 224,643,274 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42197,908,308 - 197,913,186 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12197,871,064 - 197,875,940 (-)NCBI
Celera2182,644,695 - 182,649,578 (-)NCBICelera
Cytogenetic Map2q34NCBI
RH 3.4 Map21301.7RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Tshb
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3910
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.