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Gene: Tshr (thyroid stimulating hormone receptor) Rattus norvegicus
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Symbol: Tshr
Name: thyroid stimulating hormone receptor
Description: Exhibits thyroid-stimulating hormone receptor activity. Involved in positive regulation of cell population proliferation. Localizes to membrane raft. Human ortholog(s) of this gene implicated in Graves' disease; cardiomyopathy; congenital nongoitrous hypothyroidism 1; and mitral valve prolapse. Orthologous to human TSHR (thyroid stimulating hormone receptor); PARTICIPATES IN autoimmune thyroiditis pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: thyroid stimulating hormone, receptor; thyroid-stimulating hormone receptor; thyrotropin receptor; TSH-R; TSHRA
Orthologs:
Homo sapiens (human) : TSHR (thyroid stimulating hormone receptor)  HGNC  Alliance
Sus scrofa (pig) : TSHR (thyroid stimulating hormone receptor)
Chlorocebus sabaeus (African green monkey) : TSHR (thyroid stimulating hormone receptor)
Heterocephalus glaber (naked mole-rat) : Tshr (thyroid stimulating hormone receptor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.06115,170,290 - 115,306,871 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6115,170,865 - 115,306,871 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06124,509,406 - 124,561,916 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46115,024,999 - 115,162,531 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16115,028,529 - 115,166,062 (+)NCBI
Celera6108,097,899 - 108,225,515 (+)NCBICelera
Cytogenetic Map6q31NCBI
RH 3.4 Map6759.6RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tshr
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3911
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.