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Gene: Ttpa (alpha tocopherol transfer protein) Rattus norvegicus
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Symbol: Ttpa
Name: alpha tocopherol transfer protein
Description: Exhibits vitamin E binding activity. Involved in several processes, including intracellular pH reduction; response to pH; and vitamin E metabolic process. Localizes to the cytosol and late endosome. Biomarker of liver benign neoplasm. Human ortholog(s) of this gene implicated in familial isolated deficiency of vitamin E. Orthologous to human TTPA (alpha tocopherol transfer protein); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: alpha-tocopherol transfer protein; alpha-TTP; tocopherol (alpha) transfer protein; Tocopherol transfer protein alpha; TTP
Orthologs:
Homo sapiens (human) : TTPA (alpha tocopherol transfer protein)  HGNC  Alliance
Mus musculus (house mouse) : Ttpa (tocopherol (alpha) transfer protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ttpa (alpha tocopherol transfer protein)
Pan paniscus (bonobo/pygmy chimpanzee) : TTPA (alpha tocopherol transfer protein)
Canis lupus familiaris (dog) : TTPA (alpha tocopherol transfer protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ttpa (alpha tocopherol transfer protein)
Sus scrofa (pig) : TTPA (alpha tocopherol transfer protein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0534,007,926 - 34,029,315 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0538,661,259 - 38,681,785 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4534,638,551 - 34,659,077 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1534,638,729 - 34,659,256 (+)NCBI
Celera532,573,008 - 32,593,536 (+)NCBICelera
Cytogenetic Map5q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ttpa
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3915
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.