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Gene: Ucp3 (uncoupling protein 3) Rattus norvegicus
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Symbol: Ucp3
Name: uncoupling protein 3
Description: Predicted to have oxidative phosphorylation uncoupler activity. Involved in several processes, including response to activity; response to insulin; and response to superoxide. Localizes to mitochondrion. Used to study type 2 diabetes mellitus. Biomarker of congestive heart failure; hypertension; hyperthyroidism; hypothyroidism; and prediabetes syndrome. Human ortholog(s) of this gene implicated in coronary restenosis; diabetic neuropathy; glucose metabolism disease (multiple); and obesity. Orthologous to human UCP3 (uncoupling protein 3); INTERACTS WITH (+)-catechin; ammonium chloride; amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: mitochondrial uncoupling protein 3; solute carrier family 25 member 9; UCP 3; uncoupling protein 3 (mitochondrial, proton carrier); Uncoupling protein 3 mitochondrial; Uncoupling protein 3, mitochondrial
Orthologs:
Homo sapiens (human) : UCP3 (uncoupling protein 3)  HGNC  Alliance
Mus musculus (house mouse) : Ucp3 (uncoupling protein 3 (mitochondrial, proton carrier))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ucp3 (uncoupling protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : UCP3 (uncoupling protein 3)
Canis lupus familiaris (dog) : UCP3 (uncoupling protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ucp3 (uncoupling protein 3)
Sus scrofa (pig) : UCP3 (uncoupling protein 3)
Chlorocebus sabaeus (African green monkey) : UCP3 (uncoupling protein 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01165,482,912 - 165,495,895 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1165,482,155 - 165,496,206 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01171,683,566 - 171,697,139 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41157,896,001 - 157,909,608 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11157,974,793 - 157,988,399 (+)NCBI
Celera1152,898,320 - 152,911,676 (+)NCBICelera
Cytogenetic Map1q32NCBI
RH 3.4 Map11258.1RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ucp3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3933
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.