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Gene: Vdr (vitamin D receptor) Rattus norvegicus
Symbol: Vdr
Name: vitamin D receptor
Description: Exhibits calcitriol binding activity; nuclear receptor activity; and sequence-specific DNA binding activity. Predicted to contribute to DNA-binding transcription factor activity and vitamin D response element binding activity. Involved in several processes, including cellular response to amyloid-beta; cellular response to vitamin D; and response to estradiol. Localizes to several cellular components, including T-tubule; euchromatin; and nuclear lumen. Colocalizes with caveola. Biomarker of secondary hyperparathyroidism. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hypersensitivity disease (multiple); carcinoma (multiple); liver disease (multiple); melanoma (multiple); and tuberculosis (multiple). Orthologous to human VDR (vitamin D receptor); PARTICIPATES IN altered p53 signaling pathway; tuberculosis pathway; INTERACTS WITH (+)-pilocarpine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
Also known as: 1,25-dihydroxyvitamin D3 receptor; Nr1i1; nuclear receptor subfamily 1 group I member 1; vitamin D (1,25- dihydroxyvitamin D3) receptor; Vitamin D (1,25-dihydroxyvitamin D3) receptor; Vitamin D (125-dihydroxyvitamin D3) receptor; vitamin D3 receptor
Homo sapiens (human) : VDR (vitamin D receptor)  HGNC  Alliance
Mus musculus (house mouse) : Vdr (vitamin D (1,25-dihydroxyvitamin D3) receptor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vdr (vitamin D receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : VDR (vitamin D receptor)
Canis lupus familiaris (dog) : VDR (vitamin D receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vdr (vitamin D receptor)
Sus scrofa (pig) : VDR (vitamin D receptor)
Chlorocebus sabaeus (African green monkey) : VDR (vitamin D receptor)
Heterocephalus glaber (naked mole-rat) : Vdr (vitamin D receptor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07139,344,452 - 139,394,138 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7139,342,063 - 139,394,166 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07139,536,241 - 139,585,928 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47136,567,614 - 136,617,280 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17136,644,050 - 136,693,717 (-)NCBI
Celera7125,479,125 - 125,528,679 (-)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Vdr
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3959
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.