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Gene: Wt1 (WT1 transcription factor) Rattus norvegicus
Symbol: Wt1
Name: WT1 transcription factor
Description: Exhibits sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Localizes to nucleus. Human ortholog(s) of this gene implicated in several diseases, including Denys-Drash syndrome; Frasier syndrome; malignant mesothelioma; nephroblastoma; and nephrotic syndrome type 4. Orthologous to human WT1 (WT1 transcription factor); INTERACTS WITH 2-ethoxyethanol; 2-methoxyethanol; 3,7-dihydropurine-6-thione.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Wilms tumor 1; Wilms tumor protein homolog
Homo sapiens (human) : WT1 (WT1 transcription factor)  HGNC  Alliance
Mus musculus (house mouse) : Wt1 (Wilms tumor 1 homolog)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wt1 (WT1 transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : WT1 (WT1 transcription factor)
Canis lupus familiaris (dog) : WT1 (WT1 transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wt1 (WT1 transcription factor)
Sus scrofa (pig) : WT1 (WT1 transcription factor)
Chlorocebus sabaeus (African green monkey) : WT1 (WT1 transcription factor)
Heterocephalus glaber (naked mole-rat) : Wt1 (WT1 transcription factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0395,133,221 - 95,180,574 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl395,133,713 - 95,180,564 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03101,756,056 - 101,802,601 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4390,529,704 - 90,577,280 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1390,463,925 - 90,472,651 (+)NCBI
Celera390,623,287 - 90,669,803 (+)NCBICelera
Cytogenetic Map3q33NCBI
RH 3.4 Map3720.19RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Wt1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3974
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.