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Gene: Xrcc5 (X-ray repair cross complementing 5) Rattus norvegicus
Symbol: Xrcc5
Name: X-ray repair cross complementing 5
Description: Contributes to double-stranded DNA binding activity. Involved in several processes, including cellular hyperosmotic salinity response; cellular response to X-ray; and cellular response to fatty acid. Localizes to cytoplasm; nucleus; and protein-containing complex. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease and multiple myeloma. Orthologous to human XRCC5 (X-ray repair cross complementing 5); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; INTERACTS WITH 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene; 4-hydroperoxycyclophosphamide.
Type: protein-coding
Also known as: Ku autoantigen, 80kD); Ku80; Kup80; X-ray repair complementing defective repair in Chinese hamster cells 5; X-ray repair cross complementation (double-strand-break rejoining; X-ray repair cross complementation (double-strand-break rejoining, Ku autoantigen, 80kD); X-ray repair cross-complementing protein 5
Homo sapiens (human) : XRCC5 (X-ray repair cross complementing 5)  HGNC  Alliance
Mus musculus (house mouse) : Xrcc5 (X-ray repair complementing defective repair in Chinese hamster cells 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xrcc5 (X-ray repair cross complementing 5)
Pan paniscus (bonobo/pygmy chimpanzee) : XRCC5 (X-ray repair cross complementing 5)
Canis lupus familiaris (dog) : XRCC5 (X-ray repair cross complementing 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xrcc5 (X-ray repair cross complementing 5)
Sus scrofa (pig) : XRCC5 (X-ray repair cross complementing 5)
Chlorocebus sabaeus (African green monkey) : XRCC5 (X-ray repair cross complementing 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0979,659,275 - 79,748,050 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl979,659,251 - 79,748,078 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0979,432,205 - 79,520,611 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4971,472,459 - 71,581,936 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1971,619,440 - 71,728,918 (+)NCBI
Celera971,352,925 - 71,440,328 (+)NCBICelera
Cytogenetic Map9q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Xrcc5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3976
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-05-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.