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Gene: Yy1 (YY1 transcription factor) Rattus norvegicus
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Symbol: Yy1
Name: YY1 transcription factor
Description: Exhibits sequence-specific DNA binding activity. Involved in several processes, including cellular response to interleukin-1; negative regulation of cell growth involved in cardiac muscle cell development; and regulation of transcription by RNA polymerase II. Localizes to the cytoplasm; nuclear matrix; and transcription factor complex. Used to study type 1 diabetes mellitus. Biomarker of type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human YY1 (YY1 transcription factor); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; mTOR signaling pathway; Notch signaling pathway; INTERACTS WITH 2,4-dinitrotoluene; 2-ethoxyethanol; 2-methoxyethanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: NF-E1; NMP-1; NMP1; transcriptional repressor protein YY1; UCRBP
Orthologs:
Homo sapiens (human) : YY1 (YY1 transcription factor)  HGNC  Alliance
Mus musculus (house mouse) : Yy1 (YY1 transcription factor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Yy1 (YY1 transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : YY1 (YY1 transcription factor)
Canis lupus familiaris (dog) : YY1 (YY1 transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Yy1 (YY1 transcription factor)
Sus scrofa (pig) : YY1 (YY1 transcription factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.06132,702,443 - 132,726,848 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06141,872,505 - 141,896,924 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46133,132,419 - 133,156,686 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16133,138,605 - 133,162,873 (+)NCBI
Celera6125,273,530 - 125,282,803 (+)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Yy1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 3982
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.