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Gene: Nox4em2Mcwi (NADPH oxidase 4; zinc finger nuclease induced mutant 2, Medical College of Wisconsin) Rattus norvegicus
Symbol: Nox4em2Mcwi
Name: NADPH oxidase 4; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
Description: This allele was made by zinc finger nuclease mutagenesis. The resulting mutation is an 8-bp frameshift deletion in exon 7 (del 586-593).
ASSOCIATED WITH decreased mean systemic arterial blood pressure; decreased susceptibility to hypertension; decreased urine albumin level
Type: allele  of Nox4  
Also known as: Nox4em2Mcwi
Is Marker For: Strains:   SS-Nox4em2Mcwi   SS-Nox4em2Mcwi-/-   SS-Nox4em2Mcwi-/+   SS-Nox4em2Ncf2em1Mcwi  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Cytogenetic Map1 RGD

Phenotype Annotations
References - curated


Related Rat Strains



Nucleotide Sequences

Additional Information

More on Nox4em2Mcwi
Alliance Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 4139868
Created: 2010-08-19
Species: Rattus norvegicus
Last Modified: 2010-08-19
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.