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Gene: Mir5127 (microRNA 5127) Mus musculus
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Symbol: Mir5127
Name: microRNA 5127
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: mmu-mir-5127; mu-mir-5127
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1881,992,010 - 81,992,080 (-)EnsemblGRCm38mm10GRCm38
GRCm381881,992,010 - 81,992,080 (-)NCBIGRCm38GRCm38mm10GRCm38
Celera1883,099,661 - 83,099,731 (-)NCBICelera
Cytogenetic Map18E3NCBI
cM Map1855.64NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
References - uncurated

Genomics

QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences

Additional Information

External Database Links
 
More on Mir5127
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 5134323
Created: 2011-06-28
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.