Gene: Crhr1 (corticotropin releasing hormone receptor 1) Rattus norvegicus
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Symbol: Crhr1
Name: corticotropin releasing hormone receptor 1
Description: Exhibits several functions, including G protein-coupled receptor activity, G-protein alpha-subunit binding activity, and corticotropin-releasing hormone binding activity; involved in several processes, including G protein-coupled receptor signaling pathway, learning or memory, and positive regulation of cell communication; localizes to several cellular components, including the apical part of cell, cytoplasm, and dendrite; used to study hypertension; biomarker of functional colonic disease, irritable bowel syndrome, mental depression, thromboangiitis obliterans, and type 2 diabetes mellitus; orthologous to several human genes including LINC02210-CRHR1 (LINC02210-CRHR1 readthrough); PARTICIPATES IN corticotropin-releasing hormone signaling pathway; G protein mediated signaling pathway via Galphas family; long term depression; INTERACTS WITH (R)-noradrenaline; 2,4,6-trinitrobenzenesulfonic acid; ammonium chloride.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Corticotrophin releasing hormone receptor 1; corticotropin releasing hormone 1; corticotropin-releasing factor receptor 1; corticotropin-releasing hormone receptor 1; CRF-R; CRF-R-1; CRF-R1; CRF1; CRFR-1; CRFR1; CRH-R 1; CRH-R-1; CRH-R1
Orthologs:
Homo sapiens (human) : CRHR1 (corticotropin releasing hormone receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Crhr1 (corticotropin releasing hormone receptor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Crhr1 (corticotropin releasing hormone receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CRHR1 (corticotropin releasing hormone receptor 1)
Canis lupus familiaris (dog) : LOC610380 (corticotropin-releasing factor receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Crhr1 (corticotropin releasing hormone receptor 1)
Sus scrofa (pig) : CRHR1 (corticotropin releasing hormone receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01092,191,473 - 92,233,662 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01091,953,470 - 91,995,414 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41093,312,405 - 93,354,229 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11093,326,247 - 93,368,673 (+)NCBI
Celera1087,735,518 - 87,777,693 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Crhr1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 61276
Created: 2001-01-05
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.