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Gene: Aoc1 (amine oxidase, copper containing 1) Rattus norvegicus
Symbol: Aoc1
Name: amine oxidase, copper containing 1
Description: Exhibits diamine oxidase activity and drug binding activity. Involved in several processes, including amiloride transport; cellular response to copper ion starvation; and response to antibiotic. Localizes to bicellular tight junction. Orthologous to human AOC1 (amine oxidase copper containing 1); PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine beta-hydroxylase deficiency pathway; INTERACTS WITH (R)-adrenaline; (S)-timolol (anhydrous); 1-naphthyl isothiocyanate.
Type: protein-coding
Also known as: Abp; Abp1; amiloride binding protein 1; amiloride binding protein 1 (amine oxidase, copper-containing); amiloride-binding protein; amiloride-binding protein 1; amiloride-sensitive amine oxidase; amiloride-sensitive amine oxidase [copper-containing]; amine oxidase copper domain-containing protein 1; DAO; diamine oxidase; histaminase
Homo sapiens (human) : AOC1 (amine oxidase copper containing 1)  HGNC  Alliance
Mus musculus (house mouse) : Aoc1 (amine oxidase, copper-containing 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aoc1 (amine oxidase copper containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AOC1 (amine oxidase copper containing 1)
Canis lupus familiaris (dog) : AOC1 (amine oxidase copper containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aoc1 (amine oxidase copper containing 1)
Sus scrofa (pig) : AOC1 (amine oxidase copper containing 1)
Chlorocebus sabaeus (African green monkey) : AOC1 (amine oxidase copper containing 1)
Heterocephalus glaber (naked mole-rat) : Aoc1 (amine oxidase copper containing 1)
more info ...
Is Marker For: QTLs:   Bp45   Bw10  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0478,496,043 - 78,515,582 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl478,496,043 - 78,515,584 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04143,183,686 - 143,203,225 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4476,957,477 - 76,977,643 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1477,247,444 - 77,253,779 (+)NCBI
Celera472,749,277 - 72,768,814 (+)NCBICelera
Cytogenetic Map4q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Aoc1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 61296
Created: 2001-01-05
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.