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Gene: Flt3 (Fms related receptor tyrosine kinase 3) Rattus norvegicus
Symbol: Flt3
Name: Fms related receptor tyrosine kinase 3
Description: Exhibits glucocorticoid receptor binding activity. Involved in animal organ regeneration; cellular response to glucocorticoid stimulus; and response to organonitrogen compound. Localizes to several cellular components, including cytosol; nucleus; and plasma membrane. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; acute myeloid leukemia; and prostate cancer. Orthologous to human FLT3 (fms related receptor tyrosine kinase 3); PARTICIPATES IN acute myeloid leukemia pathway; cytokine mediated signaling pathway; INTERACTS WITH 2-acetamidofluorene; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FL cytokine receptor; FMS-like tyrosine kinase 3; fms-related tyrosine kinase 3; LOC304265; receptor-type tyrosine-protein kinase FLT3
Homo sapiens (human) : FLT3 (fms related receptor tyrosine kinase 3)  HGNC  Alliance
Mus musculus (house mouse) : Flt3 (FMS-like tyrosine kinase 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Flt3 (fms related receptor tyrosine kinase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : FLT3 (fms related receptor tyrosine kinase 3)
Canis lupus familiaris (dog) : FLT3 (fms related receptor tyrosine kinase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Flt3 (fms related receptor tyrosine kinase 3)
Sus scrofa (pig) : FLT3 (fms related receptor tyrosine kinase 3)
Chlorocebus sabaeus (African green monkey) : FLT3 (fms related receptor tyrosine kinase 3)
Heterocephalus glaber (naked mole-rat) : Flt3 (fms related receptor tyrosine kinase 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0129,360,439 - 9,437,004 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl129,360,672 - 9,436,570 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01211,478,443 - 11,552,730 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4128,193,629 - 8,268,682 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1128,280,429 - 8,290,827 (+)NCBI
Celera129,364,576 - 9,437,757 (+)NCBICelera
Cytogenetic Map12p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Flt3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 61308
Created: 2001-01-05
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.