Gene: Ctsk (cathepsin K) Rattus norvegicus
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Symbol: Ctsk
Name: cathepsin K
Description: Predicted to have several functions, including collagen binding activity, cysteine-type endopeptidase activity, and fibronectin binding activity; involved in bone resorption and intramembranous ossification; localizes to the extracellular space and lysosome; biomarker of intracranial aneurysm and otitis media; orthologous to human CTSK (cathepsin K); PARTICIPATES IN rheumatoid arthritis pathway; Toll-like receptor signaling pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; (S)-amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Orthologs:
Homo sapiens (human) : CTSK (cathepsin K)  HGNC  Alliance
Mus musculus (house mouse) : Ctsk (cathepsin K)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ctsk (cathepsin K)
Pan paniscus (bonobo/pygmy chimpanzee) : CTSK (cathepsin K)
Canis lupus familiaris (dog) : CTSK (cathepsin K)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ctsk (cathepsin K)
more info ...
Is Marker For: QTLs:   Bp364  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02196,655,469 - 196,666,447 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02216,154,168 - 216,164,779 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42190,394,854 - 190,405,668 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12190,357,607 - 190,368,421 (+)NCBI
Celera2175,591,773 - 175,602,552 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ctsk
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 61810
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.