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Gene: Col1a1 (collagen type I alpha 1 chain) Rattus norvegicus
Symbol: Col1a1
Name: collagen type I alpha 1 chain
Description: Predicted to have several functions, including identical protein binding activity; platelet-derived growth factor binding activity; and protease binding activity. Involved in several processes, including cellular response to growth factor stimulus; cellular response to mechanical stimulus; and cellular response to retinoic acid. Localizes to several cellular components, including Golgi apparatus; endoplasmic reticulum; and secretory granule. Used to study cholestasis and non-alcoholic fatty liver disease. Biomarker of several diseases, including artery disease (multiple); bladder neck obstruction; liver disease (multiple); pulmonary fibrosis; and ureteral obstruction. Human ortholog(s) of this gene implicated in several diseases, including beta thalassemia; bone disease (multiple); cutaneous leishmaniasis; dermatofibrosarcoma protuberans; and tooth disease (multiple). Orthologous to human COL1A1 (collagen type I alpha 1 chain); PARTICIPATES IN acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; aminocaproic acid pharmacodynamics pathway; INTERACTS WITH (+)-schisandrin B; (R)-carnitine; (R)-lipoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha-1 type I collagen; COLIA1; collagen alpha-1(I) chain; collagen, type 1, alpha 1; collagen, type I, alpha 1; procollagen type I alpha 1; procollagen type I, alpha 1; procollagen, type 1, alpha 1; procollagen, type I, alpha 1 ; type I-alpha 1 collagen
Homo sapiens (human) : COL1A1 (collagen type I alpha 1 chain)  HGNC  Alliance
Mus musculus (house mouse) : Col1a1 (collagen, type I, alpha 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Col1a1 (collagen type I alpha 1 chain)
Pan paniscus (bonobo/pygmy chimpanzee) : COL1A1 (collagen type I alpha 1 chain)
Canis lupus familiaris (dog) : COL1A1 (collagen type I alpha 1 chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Col1a1 (collagen type I alpha 1 chain)
Sus scrofa (pig) : COL1A1 (collagen type I alpha 1 chain)
Chlorocebus sabaeus (African green monkey) : COL1A1 (collagen type I alpha 1 chain)
Heterocephalus glaber (naked mole-rat) : Col1a1 (collagen type I alpha 1 chain)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01082,745,801 - 82,762,790 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1082,745,801 - 82,762,789 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01082,563,434 - 82,580,364 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41083,622,438 - 83,639,368 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11083,636,918 - 83,653,733 (+)NCBI
Celera1078,658,450 - 78,675,438 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences