Gene: Kcnj10 (potassium voltage-gated channel subfamily J member 10) Rattus norvegicus
Symbol: Kcnj10
Name: potassium voltage-gated channel subfamily J member 10
Description: Exhibits identical protein binding activity and signaling receptor binding activity; involved in several processes, including L-glutamate import, inflammatory response, and response to corticosteroid; localizes to several cellular components, including the apical plasma membrane, astrocyte projection, and basolateral plasma membrane; used to study diabetic retinopathy; biomarker of amyotrophic lateral sclerosis, epilepsy with generalized tonic-clonic seizures, eye disease (multiple), sensorineural hearing loss, and transient cerebral ischemia; orthologous to human KCNJ10 (potassium voltage-gated channel subfamily J member 10); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ATP-sensitive inward rectifier potassium channel 10; ATP-sensitive inward rectifier potassium channel KAB-2; BIR10; BIRK1; brain-specific inwardly rectifying K(+) channel 1; inward rectifier K(+) channel Kir4.1; kir4.1; potassium channel, inwardly rectifying subfamily J member 10; potassium channel, inwardly rectifying subfamily J, member 10; potassium inwardly-rectifying channel, subfamily J, member 10
Allele / Splice: Kcnj10em1Mcwi   Kcnj10em3Mcwi  
Genetic Models: SS-Kcnj10em3Mcwi SS-Kcnj10em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01390,722,945 - 90,753,338 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01395,245,046 - 95,274,535 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41388,341,102 - 88,370,591 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11388,529,985 - 88,559,475 (+)NCBI
Celera1384,412,223 - 84,441,711 (+)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Kcnj10
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 61822
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.