Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Kcnj10 (potassium inwardly-rectifying channel, subfamily J, member 10) Rattus norvegicus
Analyze
Symbol: Kcnj10
Name: potassium inwardly-rectifying channel, subfamily J, member 10
Description: Exhibits identical protein binding activity and signaling receptor binding activity. Involved in several processes, including membrane hyperpolarization; potassium ion import across plasma membrane; and response to corticosteroid. Localizes to several cellular components, including astrocyte projection; basolateral plasma membrane; and microvillus. Used to study diabetic retinopathy. Biomarker of amyotrophic lateral sclerosis; brain disease (multiple); eye disease (multiple); and sensorineural hearing loss. Human ortholog(s) of this gene implicated in EAST syndrome and autosomal recessive nonsyndromic deafness 4. Orthologous to human KCNJ10 (potassium inwardly rectifying channel subfamily J member 10); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ATP-sensitive inward rectifier potassium channel 10; ATP-sensitive inward rectifier potassium channel KAB-2; BIR10; BIRK1; brain-specific inwardly rectifying K(+) channel 1; inward rectifier K(+) channel Kir4.1; kir4.1; potassium channel, inwardly rectifying subfamily J member 10; potassium channel, inwardly rectifying subfamily J, member 10; potassium voltage-gated channel subfamily J member 10
Orthologs:
Allele / Splice: Kcnj10em1Mcwi   Kcnj10em3Mcwi  
Genetic Models: SS-Kcnj10em3Mcwi SS-Kcnj10em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01390,722,945 - 90,753,338 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1390,723,092 - 90,752,581 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01395,245,046 - 95,274,535 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41388,341,102 - 88,370,591 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11388,529,985 - 88,559,475 (+)NCBI
Celera1384,412,223 - 84,441,711 (+)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Kcnj10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 61822
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.