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Gene: Chkb (choline kinase beta) Rattus norvegicus
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Symbol: Chkb
Name: choline kinase beta
Description: Exhibits choline kinase activity. Predicted to be involved in muscle organ development; phosphatidylcholine biosynthetic process; and phosphatidylethanolamine biosynthetic process. Human ortholog(s) of this gene implicated in intellectual disability; megaconial type congenital muscular dystrophy; muscular dystrophy; narcolepsy; and recurrent hypersomnia. Orthologous to human CHKB (choline kinase beta); PARTICIPATES IN glycerophospholipid metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aldehydo-D-glucose; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Chetk; Chkl; choline kinase-like; choline/ethanolamine kinase; choline/ethanolamine kinase beta; CK; CKB; CKEKB; EK; ethanolamine kinase
Orthologs:
Homo sapiens (human) : CHKB (choline kinase beta)  HGNC  Alliance
Mus musculus (house mouse) : Gm44502 (predicted readthrough transcript (NMD candidate), 44502)  MGI
Mus musculus (house mouse) : Chkb (choline kinase beta)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chkb (choline kinase beta)
Pan paniscus (bonobo/pygmy chimpanzee) : CHKB (choline kinase beta)
Canis lupus familiaris (dog) : CHKB (choline kinase beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chkb (choline kinase beta)
Sus scrofa (pig) : CHKB (choline kinase beta)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07130,404,818 - 130,408,813 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07130,089,639 - 130,093,008 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47127,746,749 - 127,750,104 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17127,780,978 - 127,784,334 (-)NCBI
Celera7116,973,588 - 116,976,943 (-)NCBICelera
Cytogenetic Map7q34NCBI
RH 3.4 Map7949.5RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Chkb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 61826
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.