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Gene: Kcnab1 (potassium voltage-gated channel subfamily A member regulatory beta subunit 1) Rattus norvegicus
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Symbol: Kcnab1
Name: potassium voltage-gated channel subfamily A member regulatory beta subunit 1
Description: Exhibits aldo-keto reductase (NADP) activity; ion channel binding activity; and potassium channel regulator activity. Involved in several processes, including animal organ development; myoblast differentiation; and negative regulation of delayed rectifier potassium channel activity. Localizes to the neuron projection; perikaryon; and voltage-gated potassium channel complex. Biomarker of hypertension. Human ortholog(s) of this gene implicated in temporal lobe epilepsy. Orthologous to human KCNAB1 (potassium voltage-gated channel subfamily A member regulatory beta subunit 1); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,4,6-trinitrobenzenesulfonic acid; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: K(+) channel subunit beta-1; kv-beta-1; Kvbeta1.1; Kvbeta1.2; Kvbeta1.3; KvBeta3; MGC105463; potassium channel, voltage gated subfamily A regulatory beta subunit 1; potassium channel, voltage-gated shaker related subfamily A regulatory beta subunit 1; potassium voltage gated channel shaker related subfamily beta member 1; potassium voltage gated channel, shaker related subfamily, beta member 1; potassium voltage-gated channel, shaker-related subfamily, beta member 1; voltage-gated potassium channel beta subunit; voltage-gated potassium channel subunit beta-1
Orthologs:
Allele / Splice: Kcnab1Tn(sb-T2/Bart3)2.300Mcwi  
Genetic Models: F344-Kcnab1Tn(sb-T2/Bart3)2.300Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02155,555,798 - 156,011,438 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02174,966,379 - 175,400,010 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42154,837,841 - 155,145,882 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12154,787,803 - 155,095,845 (+)NCBI
Celera2143,747,424 - 144,023,440 (+)NCBICelera
Cytogenetic Map2q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Kcnab1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 61827
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.