Gene: Gfer (growth factor, augmenter of liver regeneration) Rattus norvegicus
Analyze
Symbol: Gfer
Name: growth factor, augmenter of liver regeneration
Description: Exhibits flavin-linked sulfhydryl oxidase activity; involved in several processes, including cellular response to actinomycin D, cellular response to lipopolysaccharide, and negative regulation of cell death; localizes to the cytosol, extracellular space, and mitochondrion; used to study acute kidney failure; biomarker of acute kidney failure, cryptorchidism, and ureteral obstruction; orthologous to human GFER (growth factor, augmenter of liver regeneration); PARTICIPATES IN intermembrane space assembly pathway of mitochondrial protein import; mitochondrial iron-sulfur cluster export pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ALR; augmenter of liver regeneration; FAD-linked sulfhydryl oxidase ALR; growth factor erv1 (S. cerevisiae)-like (augmenter of liver regeneration); growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration); growth factor, erv1 -like; growth factor, erv1 homolog; growth factor, erv1 homolog (S. cerevisiae); growth factor, erv1-like (augmenter of liver regeneration)
Orthologs:
Homo sapiens (human) : GFER (growth factor, augmenter of liver regeneration)  HGNC  Alliance
Mus musculus (house mouse) : Gfer (growth factor, augmenter of liver regeneration)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gfer (growth factor, augmenter of liver regeneration)
Pan paniscus (bonobo/pygmy chimpanzee) : GFER (growth factor, augmenter of liver regeneration)
Canis lupus familiaris (dog) : GFER (growth factor, augmenter of liver regeneration)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gfer (growth factor, augmenter of liver regeneration)
Sus scrofa (pig) : GFER (growth factor, augmenter of liver regeneration)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01014,059,347 - 14,061,703 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01013,876,328 - 13,878,685 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,946,311 - 13,948,665 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11013,946,310 - 13,948,665 (-)NCBI
Celera1013,398,231 - 13,400,587 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gfer
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 61845
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.