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Gene: F10 (coagulation factor X) Rattus norvegicus
Symbol: F10
Name: coagulation factor X
CRRD ID: 61850
Description: Predicted to have phospholipid binding activity and serine-type endopeptidase activity. Involved in blood coagulation. Localizes to endoplasmic reticulum and membrane. Used to study hyperhomocysteinemia. Human ortholog(s) of this gene implicated in breast cancer and factor X deficiency. Orthologous to human F10 (coagulation factor X); PARTICIPATES IN coagulation cascade pathway; acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: coagulation factor 10; MGC108722; stuart factor
Homo sapiens (human) : F10 (coagulation factor X)  HGNC  Alliance
Mus musculus (house mouse) : F10 (coagulation factor X)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : F10 (coagulation factor X)
Pan paniscus (bonobo/pygmy chimpanzee) : F10 (coagulation factor X)
Canis lupus familiaris (dog) : F10 (coagulation factor X)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101961866 (coagulation factor X)
Sus scrofa (pig) : F10 (coagulation factor X)
Chlorocebus sabaeus (African green monkey) : F10 (coagulation factor X)
Heterocephalus glaber (naked mole-rat) : F10 (coagulation factor X)
more info ...
Allele / Splice: F10m1Mcwi   F10m2Mcwi  
Genetic Models: FHH-F10m2Mcwi FHH-F10m1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01681,803,169 - 81,822,476 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1681,803,110 - 81,822,716 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01681,288,536 - 81,307,842 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41681,327,237 - 81,346,544 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11681,327,502 - 81,346,809 (-)NCBI
Celera1674,274,866 - 74,294,173 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on F10
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 61850
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.