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Gene: Avpr1b (arginine vasopressin receptor 1B) Rattus norvegicus
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Symbol: Avpr1b
Name: arginine vasopressin receptor 1B
Description: Exhibits identical protein binding activity; peptide hormone binding activity; and vasopressin receptor activity. Involved in several processes, including cellular cation homeostasis; hyperosmotic salinity response; and positive regulation of glutamate secretion. Localizes to several cellular components, including the axon terminus; dendrite; and perikaryon. Used to study anxiety disorder and mental depression. Biomarker of alcohol dependence. Human ortholog(s) of this gene implicated in autism spectrum disorder; bipolar disorder; and mood disorder. Orthologous to human AVPR1B (arginine vasopressin receptor 1B); PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; G protein mediated signaling pathway via Galphas family; vasopressin signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: antidiuretic hormone receptor 1b; AVPR V1b; AVPR V3; V1bR; vasopressin V1b receptor; vasopressin V3 receptor
Orthologs:
Homo sapiens (human) : AVPR1B (arginine vasopressin receptor 1B)  HGNC  Alliance
Mus musculus (house mouse) : Avpr1b (arginine vasopressin receptor 1B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Avpr1b (arginine vasopressin receptor 1B)
Pan paniscus (bonobo/pygmy chimpanzee) : AVPR1B (arginine vasopressin receptor 1B)
Canis lupus familiaris (dog) : AVPR1B (arginine vasopressin receptor 1B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Avpr1b (arginine vasopressin receptor 1B)
Sus scrofa (pig) : AVPR1B (arginine vasopressin receptor 1B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01348,367,307 - 48,378,831 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1348,367,307 - 48,378,831 (+)Ensembl
Rnor_5.01353,443,235 - 53,453,450 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41344,537,103 - 44,547,318 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11344,551,145 - 44,561,361 (+)NCBI
Celera1343,384,601 - 43,396,048 (+)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Avpr1b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 61886
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.