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Gene: Avpr1b (arginine vasopressin receptor 1B) Rattus norvegicus
Symbol: Avpr1b
Name: arginine vasopressin receptor 1B
CRRD ID: 61886
Description: Exhibits identical protein binding activity; peptide hormone binding activity; and vasopressin receptor activity. Involved in several processes, including cellular cation homeostasis; hyperosmotic salinity response; and positive regulation of glutamate secretion. Localizes to several cellular components, including axon terminus; dendrite; and perikaryon. Used to study anxiety disorder and mental depression. Biomarker of alcohol dependence. Human ortholog(s) of this gene implicated in autism spectrum disorder; bipolar disorder; and mood disorder. Orthologous to human AVPR1B (arginine vasopressin receptor 1B); PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; G protein mediated signaling pathway via Galphas family; vasopressin signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: antidiuretic hormone receptor 1b; AVPR V1b; AVPR V3; V1bR; vasopressin V1b receptor; vasopressin V3 receptor
Homo sapiens (human) : AVPR1B (arginine vasopressin receptor 1B)  HGNC  Alliance
Mus musculus (house mouse) : Avpr1b (arginine vasopressin receptor 1B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Avpr1b (arginine vasopressin receptor 1B)
Pan paniscus (bonobo/pygmy chimpanzee) : AVPR1B (arginine vasopressin receptor 1B)
Canis lupus familiaris (dog) : AVPR1B (arginine vasopressin receptor 1B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Avpr1b (arginine vasopressin receptor 1B)
Sus scrofa (pig) : AVPR1B (arginine vasopressin receptor 1B)
Chlorocebus sabaeus (African green monkey) : AVPR1B (arginine vasopressin receptor 1B)
Heterocephalus glaber (naked mole-rat) : Avpr1b (arginine vasopressin receptor 1B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01348,367,307 - 48,378,831 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1348,367,307 - 48,378,831 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01353,443,235 - 53,453,450 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41344,537,103 - 44,547,318 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11344,551,145 - 44,561,361 (+)NCBI
Celera1343,384,601 - 43,396,048 (+)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Avpr1b
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 61886
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.