Gene: Tfpi (tissue factor pathway inhibitor) Rattus norvegicus
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Symbol: Tfpi
Name: tissue factor pathway inhibitor
Description: Predicted to have serine-type endopeptidase inhibitor activity; involved in cellular response to interleukin-1, cellular response to lipopolysaccharide, and response to estradiol; localizes to the extracellular space; biomarker of atrial fibrillation, disseminated intravascular coagulation, and myocardial infarction; orthologous to human TFPI (tissue factor pathway inhibitor); PARTICIPATES IN coagulation cascade pathway; syndecan signaling pathway; complement system pathway; INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: EPI; extrinsic pathway inhibitor; LACI; lipoprotein-associated coagulation inhibitor; tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
Orthologs:
Homo sapiens (human) : TFPI (tissue factor pathway inhibitor)  HGNC  Alliance
Mus musculus (house mouse) : Tfpi (tissue factor pathway inhibitor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tfpi (tissue factor pathway inhibitor)
Pan paniscus (bonobo/pygmy chimpanzee) : TFPI (tissue factor pathway inhibitor)
Canis lupus familiaris (dog) : TFPI (tissue factor pathway inhibitor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tfpi (tissue factor pathway inhibitor)
Sus scrofa (pig) : TFPI (tissue factor pathway inhibitor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0371,852,738 - 71,902,127 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0378,373,808 - 78,423,115 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4367,654,389 - 67,697,178 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1367,550,760 - 67,593,550 (-)NCBI
Celera368,890,124 - 68,933,788 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tfpi
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 61914
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.