Gene: Prkce (protein kinase C, epsilon) Rattus norvegicus
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Symbol: Prkce
Name: protein kinase C, epsilon
Description: Exhibits several functions, including SH3 domain binding activity, protein kinase C activity, and protein kinase binding activity; involved in several processes, including cellular response to platelet-derived growth factor stimulus, intracellular signal transduction, and negative regulation of apoptotic process; localizes to several cellular components, including the T-tubule, cytoplasm, and glutamatergic synapse; predicted to colocalize with the Golgi apparatus; used to study hypertension; biomarker of type 2 diabetes mellitus; orthologous to human PRKCE (protein kinase C epsilon); PARTICIPATES IN eicosanoid signaling pathway; endothelin signaling pathway; interleukin-2 signaling pathway; INTERACTS WITH (R)-adrenaline; (RS)-amphetamine; (S)-nicotine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: nPKC-epsilon; Pkce; protein kinase C epsilon type
Orthologs:
Homo sapiens (human) : PRKCE (protein kinase C epsilon)  HGNC  Alliance
Mus musculus (house mouse) : Prkce (protein kinase C, epsilon)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prkce (protein kinase C epsilon)
Pan paniscus (bonobo/pygmy chimpanzee) : PRKCE (protein kinase C epsilon)
Canis lupus familiaris (dog) : PRKCE (protein kinase C epsilon)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prkce (protein kinase C epsilon)
Sus scrofa (pig) : PRKCE (protein kinase C epsilon)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.069,483,400 - 9,973,396 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.069,404,548 - 9,883,579 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.469,631,234 - 10,097,311 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.169,631,241 - 10,097,311 (+)NCBI
Celera67,696,161 - 8,179,574 (-)NCBICelera
Cytogenetic Map6q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Prkce
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 61925
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.