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Gene: Gjb1 (gap junction protein, beta 1) Rattus norvegicus
Symbol: Gjb1
Name: gap junction protein, beta 1
Description: Exhibits gap junction channel activity. Involved in epididymis development and purine ribonucleotide transport. Localizes to gap junction; lateral plasma membrane; and protein-containing complex. Biomarker of autoimmune thyroiditis and extrahepatic cholestasis. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease X-linked dominant 1. Orthologous to human GJB1 (gap junction protein beta 1); INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: connexin 32; connexin g; connexin-32; Cx32; Cxng; GAP junction 28 kDa liver protein; gap junction beta-1 protein; gap junction membrane channel protein beta 1
Homo sapiens (human) : GJB1 (gap junction protein beta 1)  HGNC  Alliance
Mus musculus (house mouse) : Gjb1 (gap junction protein, beta 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gjb1 (gap junction protein beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GJB1 (gap junction protein beta 1)
Canis lupus familiaris (dog) : GJB1 (gap junction protein beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gjb1 (gap junction protein beta 1)
Sus scrofa (pig) : GJB1 (gap junction protein beta 1)
Chlorocebus sabaeus (African green monkey) : GJB1 (gap junction protein beta 1)
Heterocephalus glaber (naked mole-rat) : Gjb1 (gap junction protein beta 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X71,272,030 - 71,279,973 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX71,272,042 - 71,279,977 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X72,123,958 - 72,131,901 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X89,448,873 - 89,456,812 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X89,522,360 - 89,530,242 (+)NCBI
CeleraX66,857,755 - 66,865,686 (+)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gjb1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 61926
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.