Gene: Pde3a (phosphodiesterase 3A) Rattus norvegicus
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Symbol: Pde3a
Name: phosphodiesterase 3A
Description: Predicted to have 3',5'-cyclic-AMP phosphodiesterase activity. Involved in negative regulation of apoptotic process; negative regulation of cAMP-mediated signaling; and oocyte maturation. Localizes to the cytosol. Biomarker of obesity and pulmonary hypertension. Orthologous to human PDE3A (phosphodiesterase 3A); PARTICIPATES IN protein kinase A (PKA) signaling pathway; insulin signaling pathway; purine metabolic pathway; INTERACTS WITH 8-bromo-3',5'-cyclic AMP; ammonium chloride; atrazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CGI-PDE A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A; cyclic GMP-inhibited phosphodiesterase A; cyclic nucleotide phosphodiesterase; phosphodiesterase 3A cGMP inhibited; phosphodiesterase 3A, cGMP inhibited; RNPDE3A
Orthologs:
Homo sapiens (human) : PDE3A (phosphodiesterase 3A)  HGNC  Alliance
Mus musculus (house mouse) : Pde3a (phosphodiesterase 3A, cGMP inhibited)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pde3a (phosphodiesterase 3A)
Pan paniscus (bonobo/pygmy chimpanzee) : PDE3A (phosphodiesterase 3A)
Canis lupus familiaris (dog) : PDE3A (phosphodiesterase 3A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pde3a (phosphodiesterase 3A)
Sus scrofa (pig) : PDE3A (phosphodiesterase 3A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04175,431,904 - 175,703,844 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04239,659,270 - 239,921,900 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44178,658,896 - 178,930,417 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14178,904,019 - 179,175,541 (+)NCBI
Celera4162,714,211 - 162,977,642 (+)NCBICelera
Cytogenetic Map4q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pde3a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 61942
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.