Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: CREBBP (CREB binding protein) Homo sapiens
Analyze
Symbol: CREBBP
Name: CREB binding protein
Description: Exhibits several functions, including DNA binding activity; transcription coregulator activity; and transcription factor binding activity. Involved in several processes, including peptidyl-lysine acetylation; positive regulation of transforming growth factor beta receptor signaling pathway; and regulation of transcription, DNA-templated. Localizes to the cytoplasm; nuclear body; and nuclear chromatin. Implicated in Rubinstein-Taybi syndrome; acute myeloid leukemia; and precursor lymphoblastic lymphoma/leukemia. Biomarker of Huntington's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CBP; CREB-binding protein; KAT3A; MKHK1; RSTS; RSTS1
Orthologs:
Mus musculus (house mouse) : Crebbp (CREB binding protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Crebbp (CREB binding protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Crebbp (CREB binding protein)
Pan paniscus (bonobo/pygmy chimpanzee) : CREBBP (CREB binding protein)
Canis lupus familiaris (dog) : CREBBP (CREB binding protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Crebbp (CREB binding protein)
Sus scrofa (pig) : CREBBP (CREB binding protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38163,725,054 - 3,880,727 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37163,775,055 - 3,930,121 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36163,715,056 - 3,870,122 (-)NCBINCBI36hg18NCBI36
Build 34163,716,569 - 3,870,712NCBI
Celera163,981,749 - 4,136,789 (-)NCBI
Cytogenetic Map16p13.3NCBI
HuRef163,743,994 - 3,898,607 (-)NCBIHuRef
CHM1_1163,775,055 - 3,930,225 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants