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Gene: AGTR2 (angiotensin II receptor type 2) Homo sapiens
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Symbol: AGTR2
Name: angiotensin II receptor type 2
Description: The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked cognitive disability. [provided by RefSeq, Jan 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: angiotensin II receptor, type 2; angiotensin II type-2 receptor; AT2; ATGR2; MRX88; type-2 angiotensin II receptor
Orthologs:
Mus musculus (house mouse) : Agtr2 (angiotensin II receptor, type 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Agtr2 (angiotensin II receptor, type 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Agtr2 (angiotensin II receptor type 2)
Pan paniscus (bonobo/pygmy chimpanzee) : AGTR2 (angiotensin II receptor type 2)
Canis lupus familiaris (dog) : AGTR2 (angiotensin II receptor type 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Agtr2 (angiotensin II receptor type 2)
Sus scrofa (pig) : AGTR2 (angiotensin II receptor type 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X116,170,705 - 116,174,972 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X115,301,958 - 115,306,225 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X115,215,986 - 115,220,253 (+)NCBINCBI36hg18NCBI36
Build 34X115,113,884 - 115,117,702NCBI
CeleraX115,832,555 - 115,836,822 (-)NCBI
Cytogenetic MapXq23NCBI
HuRefX104,838,955 - 104,843,260 (+)NCBIHuRef
CHM1_1X115,212,791 - 115,217,059 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Protein Structures
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on AGTR2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619558
Created: 2002-07-23
Species: Homo sapiens
Last Modified: 2019-07-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.