Gene: Nt5e (5' nucleotidase, ecto) Rattus norvegicus
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Symbol: Nt5e
Name: 5' nucleotidase, ecto
Description: Exhibits 5'-nucleotidase activity and ferrous iron binding activity. Involved in several processes, including nucleobase-containing small molecule metabolic process; positive regulation of lipid biosynthetic process; and response to aluminum ion. Localizes to the cell surface and synaptic membrane. Biomarker of status epilepticus. Orthologous to human NT5E (5'-nucleotidase ecto); PARTICIPATES IN hypoxia inducible factor pathway; monoterpenoid biosynthetic pathway; niacin metabolic pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 5 nucleotidase; 5 nucleotidase ecto; 5' nucleotidase ecto; 5'-NT; 5'-nucleotidase; CD73; ecto-5'-nucleotidase; MGC112615; Nt5
Orthologs:
Homo sapiens (human) : NT5E (5'-nucleotidase ecto)  HGNC  Alliance
Mus musculus (house mouse) : Nt5e (5' nucleotidase, ecto)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nt5e (5'-nucleotidase ecto)
Pan paniscus (bonobo/pygmy chimpanzee) : NT5E (5'-nucleotidase ecto)
Canis lupus familiaris (dog) : NT5E (5'-nucleotidase ecto)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nt5e (5'-nucleotidase ecto)
Sus scrofa (pig) : NT5E (5'-nucleotidase ecto)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0895,969,002 - 96,012,733 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0895,464,591 - 95,508,322 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4893,591,630 - 93,635,481 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1893,610,734 - 93,654,911 (+)NCBI
Celera888,841,425 - 88,885,302 (+)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Nt5e
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 61956
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.