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Gene: TAC1 (tachykinin precursor 1) Homo sapiens
Symbol: TAC1
Name: tachykinin precursor 1
CRRD ID: 619560
Description: Exhibits neurokinin receptor binding activity and receptor ligand activity. Involved in several processes, including defense response to other organism; detection of temperature stimulus involved in sensory perception of pain; and regulation of neuron death. Localizes to extracellular space. Biomarker of asthma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Hs.2563; neurokinin 1; neurokinin 2; neurokinin A; neurokinin alpha; neuromedin L; neuropeptide gamma; neuropeptide K; NK2; NKNA; NPK; PPT; preprotachykinin; protachykinin; protachykinin-1; substance K; substance P; TAC2; tachykinin 2; tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)
Mus musculus (house mouse) : Tac1 (tachykinin 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tac1 (tachykinin, precursor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tac1 (tachykinin precursor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TAC1 (tachykinin precursor 1)
Canis lupus familiaris (dog) : TAC1 (tachykinin precursor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tac1 (tachykinin precursor 1)
Sus scrofa (pig) : TAC1 (tachykinin precursor 1)
Chlorocebus sabaeus (African green monkey) : TAC1 (tachykinin precursor 1)
Heterocephalus glaber (naked mole-rat) : Tac1 (tachykinin precursor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl797,732,084 - 97,740,472 (+)EnsemblGRCh38hg38GRCh38
GRCh38797,732,086 - 97,740,472 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37797,361,271 - 97,369,784 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36797,199,311 - 97,207,720 (+)NCBINCBI36hg18NCBI36
Build 34797,006,025 - 97,014,433NCBI
Celera792,055,970 - 92,064,483 (+)NCBI
Cytogenetic Map7q21.3NCBI
HuRef791,962,648 - 91,971,157 (+)NCBIHuRef
CHM1_1797,291,306 - 97,299,818 (+)NCBICHM1_1
CRA_TCAGchr7v2796,683,759 - 96,692,272 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TAC1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619560
Created: 2002-07-23
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.