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Gene: MAPK14 (mitogen-activated protein kinase 14) Homo sapiens
Symbol: MAPK14
Name: mitogen-activated protein kinase 14
CRRD ID: 619564
Description: Exhibits MAP kinase activity; mitogen-activated protein kinase p38 binding activity; and protein phosphatase binding activity. Involved in several processes, including cellular response to molecule of bacterial origin; negative regulation of hippo signaling; and regulation of cytokine production. Localizes to cytosol and nuclear speck.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CSAID-binding protein; Csaids binding protein; CSBP; CSBP1; CSBP2; CSPB1; cytokine suppressive anti-inflammatory drug binding protein; cytokine suppressive anti-inflammatory drug-binding protein; EXIP; MAP kinase 14; MAP kinase Mxi2; MAP kinase p38 alpha; MAPK 14; MAX-interacting protein 2; mitogen-activated protein kinase p38 alpha; Mxi2; p38; p38 MAP kinase; p38 mitogen activated protein kinase; p38ALPHA; p38alpha Exip; PRKM14; PRKM15; RK; SAPK2A; stress-activated protein kinase 2A
Mus musculus (house mouse) : Mapk14 (mitogen-activated protein kinase 14)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mapk14 (mitogen activated protein kinase 14)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mapk14 (mitogen-activated protein kinase 14)
Pan paniscus (bonobo/pygmy chimpanzee) : MAPK14 (mitogen-activated protein kinase 14)
Canis lupus familiaris (dog) : MAPK14 (mitogen-activated protein kinase 14)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mapk14 (mitogen-activated protein kinase 14)
Sus scrofa (pig) : MAPK14 (mitogen-activated protein kinase 14)
Chlorocebus sabaeus (African green monkey) : MAPK14 (mitogen-activated protein kinase 14)
Heterocephalus glaber (naked mole-rat) : Mapk14 (mitogen-activated protein kinase 14)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl636,027,677 - 36,111,236 (+)EnsemblGRCh38hg38GRCh38
GRCh38636,027,711 - 36,122,964 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37635,995,412 - 36,079,013 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36636,103,551 - 36,186,513 (+)NCBINCBI36hg18NCBI36
Build 34636,103,550 - 36,186,513NCBI
Celera637,550,014 - 37,633,560 (+)NCBI
Cytogenetic Map6p21.31NCBI
HuRef635,715,466 - 35,798,847 (+)NCBIHuRef
CHM1_1635,997,235 - 36,080,771 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on MAPK14
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619564
Created: 2002-07-23
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.