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Gene: SLC22A6 (solute carrier family 22 member 6) Homo sapiens
Symbol: SLC22A6
Name: solute carrier family 22 member 6
Description: Exhibits inorganic anion exchanger activity and sodium-independent organic anion transmembrane transporter activity. Involved in alpha-ketoglutarate transport; renal tubular secretion; and sodium-independent organic anion transport. Localizes to the basolateral plasma membrane and integral component of plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ55736; HOAT1; hPAHT; hROAT1; MGC45260; OAT1; organic anion transporter 1; PAH transporter; PAHT; para-aminohippurate transporter; renal organic anion transporter 1; ROAT1; solute carrier family 22 (organic anion transporter), member 6; solute carrier family 22, member 6
Mus musculus (house mouse) : Slc22a6 (solute carrier family 22 (organic anion transporter), member 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc22a6 (solute carrier family 22 member 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc22a6 (solute carrier family 22 member 6)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC22A6 (solute carrier family 22 member 6)
Canis lupus familiaris (dog) : SLC22A6 (solute carrier family 22 member 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc22a6 (solute carrier family 22 member 6)
Sus scrofa (pig) : SLC22A6 (solute carrier family 22 member 6)
Chlorocebus sabaeus (African green monkey) : SLC22A6 (solute carrier family 22 member 6)
Heterocephalus glaber (naked mole-rat) : Slc22a6 (solute carrier family 22 member 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1162,936,385 - 62,984,983 (-)EnsemblGRCh38hg38GRCh38
GRCh381162,976,597 - 62,984,967 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371162,744,069 - 62,752,495 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361162,500,645 - 62,509,045 (-)NCBINCBI36hg18NCBI36
Build 341162,500,645 - 62,509,045NCBI
Celera1160,068,114 - 60,076,514 (-)NCBI
Cytogenetic Map11q12.3NCBI
HuRef1159,073,118 - 59,081,543 (-)NCBIHuRef
CHM1_11162,626,827 - 62,635,253 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SLC22A6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619572
Created: 2002-07-23
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.