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Gene: Gstm5 (glutathione S-transferase, mu 5) Rattus norvegicus
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Symbol: Gstm5
Name: glutathione S-transferase, mu 5
Description: Exhibits glutathione transferase activity and protein homodimerization activity. Predicted to be involved in several processes, including cellular detoxification of nitrogen compound; glutathione metabolic process; and nitrobenzene metabolic process. Predicted to localize to the cytosol; intercellular bridge; and sperm fibrous sheath. Human ortholog(s) of this gene implicated in several diseases, including asthma; cystic fibrosis; larynx cancer; neurodegenerative disease (multiple); and osteosarcoma. Orthologous to human GSTM3 (glutathione S-transferase mu 3); PARTICIPATES IN glutathione conjugation pathway; glutathione metabolic pathway; phase I biotransformation pathway via cytochrome P450; INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: glutathione S-transferase Mu 5; GST class-mu 5
Orthologs:
Homo sapiens (human) : GSTM3 (glutathione S-transferase mu 3)  HGNC  Alliance
Mus musculus (house mouse) : Gstm5 (glutathione S-transferase, mu 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gstm3 (glutathione S-transferase mu 3)
Pan paniscus (bonobo/pygmy chimpanzee) : GSTM3 (glutathione S-transferase mu 3)
Canis lupus familiaris (dog) : LOC479911 (glutathione S-transferase Mu 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gstm3 (glutathione S-transferase mu 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02210,685,338 - 210,688,133 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02230,154,305 - 230,157,100 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42203,456,122 - 203,458,917 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12203,418,875 - 203,421,671 (+)NCBI
Celera2188,178,084 - 188,180,884 (+)NCBICelera
Cytogenetic Map2 NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gstm5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 61964
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.