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Gene: Kcnj5 (potassium inwardly-rectifying channel, subfamily J, member 5) Rattus norvegicus
Symbol: Kcnj5
Name: potassium inwardly-rectifying channel, subfamily J, member 5
Description: Predicted to have inward rectifier potassium channel activity and voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization. Predicted to be involved in cardiac conduction; potassium ion import across plasma membrane; and regulation of ion transmembrane transport. Localizes to T-tubule and external side of plasma membrane. Human ortholog(s) of this gene implicated in atrial fibrillation; long QT syndrome 13; and primary hyperaldosteronism. Orthologous to human KCNJ5 (potassium inwardly rectifying channel subfamily J member 5); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH 2,6-dinitrotoluene; alpha-hexachlorocyclohexane; ammonium chloride.
Type: protein-coding
Also known as: cardiac inward rectifier; CIR; G protein-activated inward rectifier potassium channel 4; GIRK-4; GIRK4; heart KATP channel; inward rectifier K(+) channel Kir3.4; KATP-1; MGC93525; potassium channel, inwardly rectifying subfamily J member 5; potassium channel, inwardly rectifying subfamily J, member 5; potassium voltage-gated channel subfamily J member 5
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0833,435,493 - 33,463,410 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl833,433,905 - 33,463,467 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0833,488,649 - 33,510,083 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4832,082,866 - 32,104,412 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1831,320,012 - 32,113,178 (-)NCBI
Celera832,183,024 - 32,204,559 (-)NCBICelera
Cytogenetic Map8q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Kcnj5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 61971
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.