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Gene: Hpd (4-hydroxyphenylpyruvate dioxygenase) Rattus norvegicus
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Symbol: Hpd
Name: 4-hydroxyphenylpyruvate dioxygenase
Description: Exhibits 4-hydroxyphenylpyruvate dioxygenase activity. Involved in tyrosine catabolic process. Localizes to the Golgi membrane; endoplasmic reticulum; and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in tyrosinemia type III. Orthologous to human HPD (4-hydroxyphenylpyruvate dioxygenase); PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine beta-hydroxylase deficiency pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 4-hydroxyphenylpyruvic acid dioxygenase; 4-hydroxyphenylpyruvic acid oxidase; 4HPPD; f Alloantigen; f protein; HPPDase
Orthologs:
Homo sapiens (human) : HPD (4-hydroxyphenylpyruvate dioxygenase)  HGNC  Alliance
Mus musculus (house mouse) : Hpd (4-hydroxyphenylpyruvic acid dioxygenase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hpd (4-hydroxyphenylpyruvate dioxygenase)
Pan paniscus (bonobo/pygmy chimpanzee) : HPD (4-hydroxyphenylpyruvate dioxygenase)
Canis lupus familiaris (dog) : HPD (4-hydroxyphenylpyruvate dioxygenase)
Sus scrofa (pig) : HPD (4-hydroxyphenylpyruvate dioxygenase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01238,828,606 - 38,839,956 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1238,828,444 - 38,839,969 (+)Ensembl
Rnor_5.01240,729,052 - 40,740,668 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41234,548,320 - 34,558,371 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11234,411,707 - 34,421,759 (+)NCBI
Celera1235,063,212 - 35,073,637 (+)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hpd
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 61974
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.