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Gene: Gna11 (G protein subunit alpha 11) Rattus norvegicus
Symbol: Gna11
Name: G protein subunit alpha 11
Description: Exhibits GTP binding activity; alkylglycerophosphoethanolamine phosphodiesterase activity; and type 2A serotonin receptor binding activity. Involved in G protein-coupled receptor signaling pathway. Localizes to cytosol and heterotrimeric G-protein complex. Human ortholog(s) of this gene implicated in autosomal dominant hypocalcemia 2 and familial hypocalciuric hypercalcemia 2. Orthologous to human GNA11 (G protein subunit alpha 11); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphaq protein family; angiotensin II signaling pathway via AT1 receptor; eicosanoid signaling pathway; INTERACTS WITH 17beta-estradiol; aldehydo-D-glucose; apocynin.
Type: protein-coding
Also known as: g alpha-11; G-protein subunit alpha-11; guanine nucleotide binding protein, alpha 11; guanine nucleotide regulatory protein G alpha 11; guanine nucleotide-binding protein alpha 11 subunit; guanine nucleotide-binding protein subunit alpha-11
Homo sapiens (human) : GNA11 (G protein subunit alpha 11)  HGNC  Alliance
Mus musculus (house mouse) : Gna11 (guanine nucleotide binding protein, alpha 11)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gna11 (G protein subunit alpha 11)
Pan paniscus (bonobo/pygmy chimpanzee) : GNA11 (G protein subunit alpha 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gna11 (G protein subunit alpha 11)
Sus scrofa (pig) : GNA11 (G protein subunit alpha 11)
Chlorocebus sabaeus (African green monkey) : GNA11 (G protein subunit alpha 11)
Heterocephalus glaber (naked mole-rat) : Gna11 (G protein subunit alpha 11)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0711,033,400 - 11,047,284 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl711,033,317 - 11,047,437 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0711,200,712 - 11,214,475 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.479,636,748 - 9,662,492 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.179,636,747 - 9,662,492 (+)NCBI
Celera76,354,654 - 6,368,340 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gna11
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619749
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.