Gene: Rac1 (Rac family small GTPase 1) Rattus norvegicus
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Symbol: Rac1
Name: Rac family small GTPase 1
Description: Exhibits several functions, including GTP binding activity, GTPase activity, and enzyme binding activity; involved in several processes, including Rac protein signal transduction, actin filament organization, and regulation of cellular biosynthetic process; localizes to the cytoplasm, dendritic spine, and intracellular organelle; predicted to colocalize with the actin filament; used to study congestive heart failure; orthologous to human RAC1 (Rac family small GTPase 1); PARTICIPATES IN Rho/Rac/Cdc42 mediated signaling pathway; Arf family mediated signaling pathway; azathioprine pharmacodynamics pathway; INTERACTS WITH (R)-mevalonic acid; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 11-deoxycorticosterone.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: p21-Rac1; ras-related C3 botulinum toxin substrate 1; ras-related C3 botulinum toxin substrate 1 (rho family small GTP binding protein Rac1); ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); rho family, small GTP binding protein Rac1
Orthologs:
Homo sapiens (human) : RAC1 (Rac family small GTPase 1)  HGNC  Alliance
Mus musculus (house mouse) : Rac1 (Rac family small GTPase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rac1 (Rac family small GTPase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RAC1 (Rac family small GTPase 1)
Canis lupus familiaris (dog) : RAC1 (Rac family small GTPase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rac1 (Rac family small GTPase 1)
Sus scrofa (pig) : RAC1 (Rac family small GTPase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01213,090,316 - 13,111,841 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01215,133,521 - 15,153,741 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,380,314 - 11,400,531 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11211,419,965 - 11,428,962 (+)NCBI
Celera1212,831,091 - 12,851,324 (+)NCBICelera
Cytogenetic Map12p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Rac1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619755
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-05-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.