Gene: Grb2 (growth factor receptor bound protein 2) Rattus norvegicus
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Symbol: Grb2
Name: growth factor receptor bound protein 2
Description: Exhibits several functions, including enzyme binding activity, epidermal growth factor receptor binding activity, and insulin receptor substrate binding activity; involved in aging and protein heterooligomerization; localizes to the protein-containing complex; orthologous to human GRB2 (growth factor receptor bound protein 2); PARTICIPATES IN insulin signaling pathway; insulin-like growth factor signaling pathway; brain-derived neurotrophic factor signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: adapter protein GRB2; Ash-psi; growth factor receptor-bound protein 2; MGC108668; protein Ash; SH2/SH3 adapter GRB2
Orthologs:
Homo sapiens (human) : GRB2 (growth factor receptor bound protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Grb2 (growth factor receptor bound protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grb2 (growth factor receptor bound protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : GRB2 (growth factor receptor bound protein 2)
Canis lupus familiaris (dog) : GRB2 (growth factor receptor bound protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grb2 (growth factor receptor bound protein 2)
Sus scrofa (pig) : GRB2 (growth factor receptor bound protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.010104,193,953 - 104,263,071 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.010104,019,823 - 104,087,251 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.010104,735,560 - 104,738,091 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410105,722,014 - 105,818,649 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110105,737,088 - 105,833,269 (-)NCBI
Celera1099,455,840 - 99,524,352 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Grb2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 619758
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.